Why Alternative Cancer Treatment

On Animal Models of Human Disease in Cancer Research

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partially quoted from the New Zealand Anti-Vivisection Society’s “1999 Cancer Research Review” and continued from What The Vested Interest Groups Say About Animal Models of Human Disease in Cancer Research

Bayer ceased their studies of MMPIs for cancer treatment after failure in human patients. Bayer's director of oncology research, Dr. Mel Sorensen said: 'the finding was very surprising to us and contrary to preclinical [animal] data which confirmed the drug inhibited tumors in rodents.’
Reuters Health, 27 September 1999

“The use of animals in cancer research has been attacked as unnecessary cruelty to animals, and defended as absolutely essential for research progress....From a scientific standpoint, what is pertinent is that what are called 'animal model systems' in cancer research have been a total failure....The moral is that animal model systems not only kill animals, they also kill humans. There is no good factual evidence to show that the use of animals in cancer research has led to the prevention or cure of a single human cancer.”
Dr. Irwin D. Bross Ph.D. writing in "Animals in Cancer Research: A Multi-Billion Dollar Fraud", reproduced in Fundamental and Applied Toxicology, November 6 1982. “This article exposes that cancer research using animals is a highly profitable undertaking for certain medical schools and research institutes that are incapable of doing genuine cancer research - and that the use of animals is sustained by what Dr Bross says is a ‘superstitious belief in a grossly unscientific notion that mice are miniature men’.”

"It is not possible to apply to the human species, experimental information derived from inducing cancer in animals."
Dr Kenneth Starr, Hon. Director of the New South Wales Cancer Council, Sydney Morning Herald, 7 April 1960.

…the disease we know as "cancer" is actually an umbrella term for about 200 diseases that afflict humans exclusively. In other words, these 200 diseases are distinctly human cancers. Some of these cancers can be seen in other animals, but the specific characteristics of these animal cancers differ greatly from that in human cancer.

Most nonhuman cancers arise in the bone, connective tissue or muscle. In contrast, most human cancers arise in living membranes.

Cancer in animals simply does not mimic the human form of the disease. That is why Dr. Richard Klausner of the National Cancer Institute stated in an LA Times article on May 6, 1998: "The history of cancer research has been a history of curing cancer in the mouse. We have cured mice of cancer for decades, and it simply didn't work in humans."
from Animals & Scientific Research: Cancer Research by www.navs.org

"The fact that experiments failed to demonstrate any carcinogenic activity in animals does not exclude the possibility of a carcinogenic effect in man."
British Medical Journal, 10 September 1955, p. 692

"It is time to end cancer research on animals because it is not related to humans."
Dr A. Sabin

"The characteristic effects in leukemia were detected solely as a result of clinical observation. The various leukemias in the mouse and rat were relatively refractory to the influence of urethane, and the remarkable effect in the human might have eluded discovery if attention had been directed to the animal alone. That illustrates the hazards of such work."
Prof. Alexander Haddow, British Medical Journal, 2 December 1950, page 1272.

"The drugs Prednisone and Vincristine are often hailed as 'curing' childhood leukemia. Both drugs were rejected by the US National Cancer Institute as 'useless' on the basis of animal tests.

Prednisone was developed as a result of clinical observation of the effects of adrenal extract. Vincristine is an alkaloid of 'Vincra Rosea', a type of periwinkle plant, and extracts of periwinkle were used in the Roman Empire to 'dry tumors' (Pliny).

They were eventually brought to clinical trials. The children cured of leukemia owe their lives to clinical observations and trials — and not to the animal 'model'."
Brandon Reines, DVM, Cancer Research on Animals: Impact and Alternatives.

"Sir, In arguing for the health benefits of Enzogenol, an antioxidant supplement, Kelvin Duncan appears to dismiss the value of well conducted clinical trials on humans as an expensive standard of proof. Instead he seems to be willing to extrapolate the results of animal experiments directly to humans and to generalise from his own subjective experience with Ezogenol. All this from the Dean of Science at Canterbury University"
Dr Lynette Murdoch, Dr Tim Wilkinson, Letter to the Editor, The Press, 28 July 1998, page 4.

“[S]mall differences between man and [dogs] have littered medical history with catastrophes when discoveries in dogs have been applied to man. For example:

Most of us have come to grips with the idea that smoking causes cancer, at least in man. Dogs are however extremely resistant to the cancer-causing effects of cigarette smoke. The tobacco companies were able to hide behind science's inability to reproduce the obvious in dogs for many, many years and used such research to ‘prove’ that smoking was not unhealthy.

Because [cancer] creates so much fear and distress, whenever vivisectors seek to justify their butchering, the stock response is that 'We must experiment on animals to find the cure for cancer'.

However, after so much time, after so many animals have been slaughtered in 'cancer research', and after so much money has been given to cancer research, one naturally wonders why so many people continue to be afflicted by, and die from cancer.

In fact this is hardly surprising in view of the animals used in this pseudo-research. When vivisectors induce cancer in laboratory animals (primarily mice and rats), the cancer-causing substance gives different results, not only from species to species, but also from one strain to another of the same species. For example:

  • In the mouse strain C3HF, urethane gives rise to hepatomas, tumours of the reticuloendothelium and lung tumours. And yet in the mouse strain C57B1, urethane causes lymphomas of the thymus. However, in humans, urethane is a good remedy in treating leukaemia.
  • Dimethyl-benzo-alpha-anthracene causes lymphomas in mice of the 'Swiss' strain, but produces bronchial adenomas (benign tumours) in the 'Strong A' strain of mice; in other mouse strains, it produces liver tumours (but only in the males).
  • Benzol and arsenic, both carcinogenic in humans, are not so in any of the rodent species used for experiments. 2-naphthyl is carcinogenic for the human bladder, but does not cause any form of cancer in mice.
  • Benzidine causes bladder cancer in human beings, but in mice it causes a neuroma of the acoustic nerve and intestinal and liver cancer.
  • Carbon tetrachloride (CCl4) produces liver cancer in the mouse but causes cirrhosis of the liver in rats.
  • 4-amino-diphenyl causes bladder cancer in humans and yet in the mouse it results in mammary cancer.
  • Chloroform (CHCl3) gives rise to liver cancer in the females of various strains of mice, but not in the males.
  • Isonicotine hydrazine (INH), or isoniazid, causes adenomas (benign) and bronchial adenocarcinomas (malignant) in different strains of mice, but nothing similar has been found in human beings despite being used for treating TB over the last forty years.

The fact that there are acknowledgements that the end of cancer is nowhere in sight is further evidence of the fraud and futility of vivisection.”
South Africans for the Abolition of Vivisection

Animal experiments guarantees full employment, for once begun, a career in animal experiments is assured. It is as good as a pension... What is science today? A narrow and hard specialization for profit, exploitation and domination.
Dr med. Herbert Stiller, specialist in neurology & psychiatry, psychotherapy, Dr med. Margot Stiller, psychologist, specialist in neurology and psychiatry, psychotherapy, in "Animal Experimentation and Animal Experimenters"

“Animal research does not work, as every species of animal is a different biomechanical and biochemical entity. Nonhuman animals are different not only from humans, but also from each other: anatomically, physiologically, immunologically, genetically and histologically.

Animals react differently to different drugs, vaccines and chemical substances, not only from humans but also from each other. Aspirin kills cats and penicillin kills guinea pigs. Yet guinea pigs can safely eat strychnine — one of the deadliest poisons for humans but not for monkeys.

Human diseases cannot be recreated in animals because once a disease is ‘recreated’ it is artificial and no longer the original, natural disease that the body itself produced.

Our environment — air, land, water and food supplies — is being systematically destroyed by thousands of pesticides and toxicants that no matter how destructive are routinely and conveniently found safe and thus allowed to be marketed based on inherently invalid and misleading animal tests.”
1999 Cancer Research Review

It is estimated that in the United States of America 33% of people will be diagnosed with cancer during their lifetime. The incidence of cancer in USA has gone up 18 percent and the death rate 7 percent since President Nixon declared the "war on cancer" in 1971. After spending billions of dollars and decades of massive effort not only has cancer not been stopped but also its incidence has increased.
SUPRESS, "Cancer: Losing a war that could easily be won", The Vanguard, reprinted in The Guardian Newsletter (Australia), Vol. 3, No. 10, Spring 1997.

"During the past fifty years scientists experimenting with thousands of animals have found 700 ways of causing cancer. But they had not discovered one way of curing the disease."
Dr J.F. Brailsford M.D., Ph.D, Birmingham Evening Dispatch, U.K., January 10 1956.

"My overall assessment is that the national cancer programme must be judged a qualified failure."
Dr John Bailer, who spent 20 years on the staff of the U.S. National Cancer Institute and was editor of its journal, speaking at the Annual Meeting of the American Association for the Advancement of Science in May 1985.

"The five year cancer survival statistics of the American Cancer Society are very misleading. They now count things that are not cancer, and because we are able to diagnose at an earlier stage of the disease, patients falsely appear to live longer.

Our whole cancer research in the past 20 years has been a failure. More people over 30 are dying from cancer than ever before... More women with mild or benign diseases are being included in statistics and reported as being 'cured'. When government officials point to survival figures and say they are winning the war against cancer they are using those survival rates improperly."
Dr John Bailer

"For thirty-five years U.S. scientists labouring in the National Cancer Institute's screening programme have injected more than 400,000 chemicals into leukaemic mice hoping to find chemotherapies that would help solve the riddles of cancer... We've been using the wrong system as the screening device."
David Korn, Chairman of the National Cancer Institute Advisory Board, "Giving Up on the Mice. Scientists Searching for Cancer-cures Try A New Tactic", Time Magazine, September 17 1990.

“Due to the use of animals, cancer research has been a failure.”
1999 Cancer Research Review

“Cancer research on laboratory animals is prolific yet does not produce valid or useful results. It is generally accepted that a large proportion of cancers are preventable, yet funding for research into prevention is disproportionate. Meanwhile despite the emphasis on research for treatment, research funds and facilities are not made available for those who wish to study natural or holistic therapies.”
1999 Cancer Research Review

"Almost all biomedical research being conducted today, including cancer research, is based on the animal model of human disease. Predictably the absurd concept that spontaneous diseases can be recreated in the laboratory and that human medicine can be based on veterinary medicine has brought us increases in both the incidences and death rates in practically all diseases, including cancer."
SUPRESS, "Cancer: Losing a war that could easily be won", The Vanguard, reprinted in The Guardian Newsletter (Australia), Vol. 3, No. 10, Spring 1997.

"Screening of over half a million compounds as anti-cancer agents on laboratory animals between 1970–85, only 80 compounds moved into clinical trials on humans. Of these only 24 had any anti-cancer activity and only 12 appeared to have a "substantial clinical role". But these so-called "new" active agents were not so new: they are analogues of chemotherapeutic agents already known to work in humans."
Ronald Allison M.D., quoted in Physicians Committee for Responsible Medicine, Vol. 8, No. 1, 1992, page 6

"Despite the general recognition that 85 per cent of all cancers is caused by environmental influences, less than 10 percent of the (U.S.) National Cancer Institute budget is given to environmental causes. And despite the recognition that the majority of environmental causes are linked to nutrition, less than one per cent of the NCI budget is devoted to nutrition studies. And even that small amount had to be forced on the Institute by a special amendment of the National Cancer Act in 1974."
Hans Ruesch, Naked Empress, CIVIS, Switzerland, 1992, page 77.

"According to the U.S. National Cancer Institute, approximately 80% of all cancers are preventable."
Moneim A. Fadali, M.D., USA, Animal Experimentation A Harvest of Shame, 1996, page 17.

"A shift in research emphasis from research on treatment to research on prevention is necessary if substantial progress against cancer is to be forthcoming".
"Progress Against Cancer", New England Journal of Medicine, Vol. 314, page 1226, 1986.

"Despite the present emphasis on research of treatment rather than prevention holistic cancer treatment is never given a fair go anywhere in the Western world. There is no level playing field on which holistic health practitioners can work on equal terms with the Cancer Establishment. Well-documented systems offering revolutionary possibilities of cure have been offered to the world's Cancer Establishment and rejected without a fair trial."
Chris Wheeler, "Who owns cancer?", The Self-Help Cancer Cure Book, Soil & Health, 1997, page 12.

"Natural Therapies are not scientifically proven to give better results than conventional treatment. Those controlling research funds and facilities give nothing to natural therapists to prove their case. In rare cases that natural remedies have been investigated by conventional medical institutions, it was done in such a way that a negative outcome was guaranteed."
Walter Last, "Scientific cancer treatment?", The Self-Help Cancer Cure Book, Soil & Health, 1997.

“Future research should be restricted to valid methods such as epidemiology. To help humans we need to study the cancers that occur in humans not in other animals in laboratory conditions.

One of the most natural ways of studying cancer in humans is that of observation. Observing what occurs spontaneously in as great a number of human models as possible scattered throughout the world. Epidemiology includes this kind of observation. This knowledge can enable preventative measures to be taken against cancers.

Epidemiology is not used more often as it does not give instant, extravagant returns. It takes time, demanding sincere participation and cooperation on the local, national and international level. But fortunately in these days of computers and hi-tech global communications gathering data readily available in health institutions worldwide can facilitate epidemiology's job. Surely epidemiology must be looked upon as one of the key areas of future growth in cancer research.”
1999 Cancer Research Review

“Study should be made of cancer being caused by animal research.”
1999 Cancer Research Review

“The contents of many laboratories represent a bizarre cocktail of viruses, biological reagents, chemicals, cancer agents and different species of animal.

In 1986 the Institut Pasteur set up an external commission of inquiry to investigate three cases of bone cancer among staff at the same laboratory at the Institut. Two of those affected had died that year, and colleagues suspected that the cases might be linked to work on oncogenic viruses. One of the fatalities had been working on a project to bring about the transformation of mouse embryo carcinoma cells.

In 1987, the London Hazards Centre reported that in at least one school, carcinogenic fumes have been regularly released into the classroom by the methods used to soften rats' brains for dissection.”
Biohazard — the Silent Threat from Biomedical Research, National Anti-Vivisection Society (U.K.), 1987.

“The use of animals in toxicological testing allows chemicals to be released or to remain on the market even though they may cause cancer in humans.
Because animal tests are so ambiguous, studies are often repeated; debates over test results are so drawn out that regulation is delayed. Products typically remain on the market until decisions are reached.

Even when positive human toxicity data are available, as in the case of benzene and DDT, chemicals are not withdrawn. Regulatory scientists habitually seek to confirm human findings in animals before regulatory steps are taken.

For further information on the dangers of toxicity testing on animals and valid methods that can be used, refer Alix Fano, Lethal Laws — Animal Testing, Human Health and Environmental Policy, Zed Books, 1998.”
1999 Cancer Research Review

“Cancer caused by vivisection-based farming.
Vivisection and Farming... The Connection
Antibiotics, growth hormones, drenches, vaccinations, worm-killing chemicals, weight- and profit-producing drugs, pesticides, insecticides, tranquillisers, fungicides are all tested on animals.”
1999 Cancer Research Review

"Of the 143 drugs and pesticides identified as likely to leave residues in raw meat and poultry, forty-two are known to cause or are suspected of causing cancer; twenty of causing birth defects and six of causing mutations."
Jim Mason, Brave New Farm

"Cancer Prevention
A vegetarian diet helps prevent cancer. Studies of vegetarians show that death rates from cancer are only about one-half to three-quarters of those of the general population. Breast cancer rates are dramatically lower in countries where diets are typically plant-based. When people from those countries adopt a Western, meat-based diet, their rates of breast cancer soar.

Vegetarians also have significantly less colon cancer than meat eaters. Meat consumption is more closely associated with colon cancer than any other dietary factor.

Why do vegetarian diets help protect against cancer? First, they are lower in fat and higher in fiber than meat-based diets. But other factors are important, too. For example, vegetarians usually consume more of the plant pigment beta-carotene. This might help to explain why they have less lung cancer. Also, at least one study has shown that natural sugars in dairy products may raise the risk for ovarian cancer in some women.

Some of the anti-cancer aspects of a vegetarian diet cannot yet be explained. For example, researchers are not quite sure why vegetarians have more of certain white blood cells, called ‘natural killer cells,’ which are able to seek out and destroy cancer cells."
Physicians Committee for Responsible Medicine, Vegetarian Starter Kit

"Responsible for causing leukemia and fatal aplastic anaemia in human beings. Damage not predicted by animal experiments."
Ralph Heywood, 1990, speaking on the drug Chloramphenicol which caused human cancers in spite of having been sanctioned by vivisection.

"Extensive experiments on dogs failed to show evidence of injury or disease to the canine species."
Bulletin, Easton, Massachusetts, 2 April 1953, speaking on the drug Chloramphenicol which caused human cancers in spite of having been sanctioned by vivisection.

“Tagamet (Cimetidine)
Produced by SmithKline & French in 1977 after extensive testing on dogs, rabbits, hamsters, mice and rats, none of which gave signs of stomach cancer. By 1981 the British Committee for the Safety of Medicine had received 2,459 reports of adverse reactions which includes headaches, dizziness, skin disorders, psychiatric disorders, liver disorders, tremor, abdominal pain, nausea and diarrhoea and 21 reports of stomach cancer.”
1999 Cancer Research Review

"Despite there being no signs of stomach cancer in animals on which the drug was tested, there could be an increased risk of stomach cancer on the human patients to whom it is prescribed."
Reed et al., Lancet, Vol. 2, 12 September 1981, page 550

"Diethylstilbestrol, tested without adverse effects on animals for years, caused cancer in girls whose mothers had been prescribed the drug in pregnancy. Hundreds of women developed vaginal cancer because their mothers were given DES in pregnancy."
Time Magazine, 23 March 1980.

(“In the 1960s two and a half million New Zealanders were vaccinated with contaminated monkey-based polio vaccine.”):
"It cannot be ruled out that two million New Zealanders could not be suffering in thirty years' time from cancerous brain tumours as a result of the vaccinations."
Dr A. Malcolme, then Minister of Health

“A recent study by Dr Janet Butel published in the Journal of the National Cancer Institute, USA, suggests that the SV40 cancer causing virus which contaminated the polio vaccine are being passed from those given the contaminated vaccine to their children.

According to Professor Gordon McVie, the director general of the Cancer Research Campaign (U.K.), researchers have so far uncovered evidence linking SV40 to a number of cancers, including brain tumours and bone cancer.”
1999 Cancer Research Review

"I've a feeling that the virus might be implicated in more, such as non-Hodgkin lymphoma and prostate cancer", he said.
Sunday Telegraph (U.K.), 14 February 1999, page 7.

"From a scientific standpoint, what is pertinent that what are called 'animal model systems' in cancer research have been a total failure... Not a single essential new drug for the treatment of human cancer was first picked up by an animal model system... Thus the tens of millions of animals killed in the mass screening for new cancer drugs died in vain...

...the results of animal model systems for drugs or other modalities have done nothing but confuse and mislead the cancer researchers who have tried to extrapolate from mice to man. Moreover, when they have been used to guide clinical research they have sent investigators on one long and costly wild goose chase after another.

Thus, scientifically speaking, the animal studies are a fraud. Privately, they [vivisectors] will concede that animal models don't work, but they shrug this off because nothing works.

Two high-powered promoters were pushing a study which used a particular drug called '5-FU'. They presented animal data to support their claims for using this drug on human breast cancer. In our studies which included 5-FU, the doctors had unanimously decided to drop it because there was no sign of benefit but very serious toxicity...

My efforts to head off the poisoning of hundreds of women with breast cancer, with a dangerous drug that could destroy their host defence systems failed. The National Cancer Institute went right ahead with its plan to fund this deadly study and others like it. Not a few women with breast cancer have paid with their lives for this stupidity... animal model systems not only kill animals, they also kill humans."
Cancer research scientist Irwin Bross, Ph.D, Director of Biostatistics, Roswell Park Memorial Institute, New York, in "Animals in Cancer Research: a Multi-Billion Dollar Fraud".

"Cancer research is the flagship of vivisection, using a quarter of a million animals, in the UK alone, each year."

"Between 1990 and 1997, USDA registered research laboratories reported killing at least 12,892,885 dogs, cats, primates, guinea pigs, hamsters, rabbits, farm animals, bears, armadillos, squirrels, wild rodents, and other "covered" species. This figure does not include hundreds of millions of rats, mice, frogs, or birds, nor does it include any animals killed at non-USDA registered experimentation labs."

Everyone should know that most cancer research is largely a fraud and that the major cancer research organisations are derelict in their duties to the people who support them.
Linus Pauling Ph.D. (1901–1994), two times Nobel Prize winner

"For over two hundred years the inmates of the vivisection laboratories have tormented to death hundreds of millions of animals. Over 800 ways of inducing tumours in animals have been found, not one of which is remotely related to a cancer which has developed spontaneously in a human.

Tumours are implanted under the skin, and then observed as the growth takes over the body, animals are radiated, limbs become gangrenous and fall off, force-feeding large amounts of toxic substances causes vomiting and fits — until death intervenes...

Animal-based 'cancer research' fund-raisers include: Cancer Research UK (formerly The Imperial Cancer Research Fund and The Cancer Research Campaign), The Leukaemia Research Fund, Tenovus Cancer Research, The Yorkshire Cancer Research Campaign, Cancer and Leukaemia in Childhood Trust, Institute of Cancer Research, World Cancer Research Fund.

If you support animal-based 'cancer research' you are supporting the biggest fraud, medical or otherwise, in history, and the cruel and senseless torture and killing of your fellow beings; both human and animal."
British Anti-Vivisection Association

"The greatness of a nation and its moral progress can be judged by the way its animals are treated."

"Not to hurt our humble brethren is our first duty to them, but to stop there is not enough. We have a higher mission — to be of service to them wherever they require it."
St. Francis of Assisi

"I am in favor of animal rights as well as human rights. That is the way of a whole human being."
President Abraham Lincoln, 1809–1865

"I have from an early age abjured the use of meat. And the time will come when men such as I will look upon the murder of animals the way we now look upon the murder of men."
Leonardo Da Vinci, 1452–1519

"Animals are my friends...I don't eat my friends."
George Bernard Shaw

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